Sweet solution
نویسنده
چکیده
Sugar pills are usually placebos, but Smith et al. (2002, this issue) use one to rescue designer mice unable to make GDP-Fucose. Dietary fucose enters a salvage pathway and spares the mice. Sound simple? Not so. Unknown genetic factors determine life or death.
منابع مشابه
Same genetic components underlie different measures of sweet taste preference.
BACKGROUND Sweet taste preferences are measured by several often correlated measures. OBJECTIVE We examined the relative proportions of genetic and environmental effects on sweet taste preference indicators and their mutual correlations. DESIGN A total of 663 female twins (324 complete pairs, 149 monozygous and 175 dizygous pairs) aged 17-80 y rated the liking and intensity of a 20% (wt/vol...
متن کاملInfluence of sweet suppressing agent on gustatory brain evoked potentials generated by taste stimuli.
A measurement system was employed to detect gustatory evoked potentials from human scalp by stimulus of a taste solution with the use of a laser beam device. The evoked potentials for four taste qualities (i.e., sweet-sucrose, salty-sodium chloride, sour-tartaric acid, and bitter-quinine-HCl) were measured before and after treatment with a sweet suppressing agent (i.e., gymnema sylvestre extrac...
متن کاملEffect of non-sucrose sweet tasting solution on neonatal heel prick responses.
A substance commercially described as 'sugar free,' used as a sweetener for paracetamol suspension, was evaluated on measures of neonatal pain. Sixty infants were randomly allocated to receive one of four solutions before heel stab blood sampling: sterile water (placebo); 25 or 50% sucrose (weight/volume); and the commercial sweet-tasting solution. There was a significant reduction in crying ti...
متن کاملEffects of Drugs, Sex, and Age on Preference to Sweet Taste in Rats
The preference of sweet taste in rats is a phenomenon that is influenced by many factors. Drugs, sex, and age are three important aspects to consider when determining the underlying mechanisms that influence increased intake in the presence of sweet taste. Research has shown that drugs acting on receptors and neurotransmitters of brain mechanisms relevant to hedonic and reinforcement effects ca...
متن کاملPatterns of Sweet Taste Liking: A Pilot Study
Two distinct patterns of sweet taste liking have been described: one showing a peak liking response in the mid-range of sucrose concentrations and the other showing a monotonic liking response at progressively higher sucrose concentrations. Classification of these patterns has been somewhat arbitrary. In this report, we analyzed patterns of sweet taste liking in a pilot study with 26 adults inc...
متن کاملFunctional magnetic resonance imaging of human hypothalamic responses to sweet taste and calories.
BACKGROUND Evidence exists that beverages do not trigger appropriate anticipatory physiologic responses, such as cephalic phase insulin release. Therefore, it is of interest to elucidate the food properties necessary for triggering adaptive responses. Previously, we found a prolonged dose-dependent decrease in the hypothalamic functional magnetic resonance imaging signal after ingestion of a gl...
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ورودعنوان ژورنال:
- The Journal of Cell Biology
دوره 158 شماره
صفحات -
تاریخ انتشار 2002